Description

2-tert-Butyl-5-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a sterically hindered tert-butyl group and a reactive chlorine atom, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and organocatalysts, facilitating challenging chemical transformations.
• Material Science Research: Intermediate in the production of advanced organic materials, such as liquid crystals, organic semiconductors, and photoactive compounds.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	2-tert-Butyl-5-Chloropyridine
CAS No.	56029-44-8
Molecular Formula	C9H12ClN
Molecular Weight	169.65 g/mol
Synonyms	5-Chloro-2-tert-butylpyridine; 2-(1,1-Dimethylethyl)-5-chloropyridine; 5-Chloro-2-(tert-butyl)pyridine; 2-tert-Butyl-5-chloropyridine; 2-(tert-Butyl)-5-chloropyridine; 5-Chloro-2-(1,1-dimethylethyl)pyridine; Pyridine, 5-chloro-2-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-5-Chloropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.