Description

Prosta-8(12),13-Dien-1-Oic Acid, 9-(Methoxyimino)-15-[(Trimethylsilyl) Oxy]-, Trimethylsilyl Ester, (13E,15S)- is a sophisticated, high-purity synthetic prostaglandin derivative, specifically designed as a key protected intermediate for advanced pharmaceutical research and synthesis. Its value lies in its precise stereochemistry and protective groups, which enable controlled, high-yield reactions in the production of complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing next-generation therapeutics, particularly in areas like inflammation, immunology, and reproductive health.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of prostaglandin analogs and related therapeutic agents.
• Biochemical Research: Used as a reference standard or precursor in studies investigating prostaglandin pathways, receptor binding, and signal transduction.
• Process Chemistry: Serves as a protected intermediate in multi-step organic synthesis, allowing for selective reactions in complex molecule assembly.
• Drug Discovery & Development: Employed in medicinal chemistry programs to create novel drug candidates targeting inflammation, pain, and cardiovascular conditions.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized, high-value compounds for academic and industrial research partnerships.

Basic Information

Product Name	Prosta-8(12),13-Dien-1-Oic Acid, 9-(Methoxyimino)-15-[(Trimethylsilyl) Oxy]-, Trimethylsilyl Ester, (13E,15S)-
CAS No.	56009-43-9
Molecular Formula	C27H49NO4Si2
Molecular Weight	507.86 g/mol
Synonyms	9-(Methoxyimino)-15-[(trimethylsilyl)oxy]prosta-8(12),13-dien-1-oic acid trimethylsilyl ester; (13E,15S)-9-(Methoxyimino)-15-(trimethylsilyloxy)prosta-8(12),13-dien-1-oic Acid Trimethylsilyl Ester; Prostaglandin Intermediate 56009-43-9; 15-TMS-ether, 1-TMS-ester of 9-Methoxyimino PGD derivative; Protected Prostaglandin D Analog; Trimethylsilyl 9-(methoxyimino)-15-(trimethylsilyloxy)prosta-8(12),13-dien-1-oate; (13E,15S)-Isomer of Prostaglandin Silyl Ether Ester.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, GC, NMR, and IR spectroscopy. Our quality protocols are designed to meet the exacting standards required for pharmaceutical R&D and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Purity (GC)	≥ 95.0% (Area %)
Isomeric Purity ((13E,15S)-Isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.