Description

n-(3-Methyl-1-Oxobutyl)Glycine Methyl Ester is a high-purity, protected amino acid derivative, specifically a leucine derivative with a methyl ester group. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure and functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and advanced biochemical research.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in the study of enzyme-substrate interactions, metabolic pathways, and protein structure-function relationships.
• Proteomics & Diagnostics: Employed in the development of peptide probes, biomarkers, and diagnostic assay components.
• Agrochemical Research: Potential intermediate in the development of novel, biologically active compounds for crop protection.
• Material Science: Can be utilized in the creation of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	n-(3-Methyl-1-Oxobutyl)Glycine Methyl Ester
CAS No.	56009-37-1
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-(3-Methyl-1-oxobutyl)glycine methyl ester; Methyl 2-[(3-methylbutanoyl)amino]acetate; N-(3-Methylbutanoyl)glycine methyl ester; N-Isobutyrylglycine methyl ester (common name); Leucine derivative methyl ester; Boc-Leu-OH methyl ester analog; Protected leucine glycine ester
EINECS	Contact for details

Quality Control

Our n-(3-Methyl-1-Oxobutyl)Glycine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.