Description

Methyl 3-Chloro-2-Fluoropropionate is a high-value fluorinated building block essential for advanced organic synthesis. This compound is prized for its bifunctional reactivity, offering both an electrophilic site and an ester group for further transformations. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor in the synthesis of fluorinated liquid crystals and specialty electronic materials.
• Organic Synthesis Building Block: Employed in various coupling reactions, nucleophilic substitutions, and as a precursor for other fluorinated esters and acids in fine chemical production.
• Material Science Research: Utilized in academic and industrial R&D for creating novel polymers and functional materials with specific properties.

Basic Information

Product Name	Methyl 3-Chloro-2-Fluoropropionate
CAS No.	55900-27-1
Molecular Formula	C4H6ClFO2
Molecular Weight	140.54 g/mol
Synonyms	Methyl 3-chloro-2-fluoropropanoate; 3-Chloro-2-fluoropropionic Acid Methyl Ester; 2-Fluoro-3-chloropropionic Acid Methyl Ester; Methyl 2-fluoro-3-chloropropionate; Propanoic acid, 3-chloro-2-fluoro-, methyl ester; Methyl β-chloro-α-fluoropropionate
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2-Fluoropropionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for research and industrial synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.