Description

2-Methyl-2-(Trifluoroacetylamino)Propionic Acid (R)-sec-Butyl Ester is a high-value chiral building block and synthetic intermediate characterized by its trifluoroacetyl-protected amino acid ester structure. This compound is essential for facilitating complex organic syntheses, particularly in the development of pharmaceuticals and advanced materials, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily sought by research institutions and industrial manufacturers engaged in the production of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Peptide Mimetics & Modifications: Serves as a protected amino acid derivative for constructing peptide analogs with enhanced metabolic stability.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric catalysis.
• Material Science: A precursor for specialty polymers and advanced organic materials requiring fluorinated components.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	2-Methyl-2-(Trifluoroacetylamino)Propionic Acid (R)-sec-Butyl Ester
CAS No.	55887-90-6
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	(R)-2-Methyl-2-((2,2,2-trifluoroacetyl)amino)propanoic acid sec-butyl ester; (R)-N-(Trifluoroacetyl)-α-methylalanine sec-butyl ester; (R)-sec-Butyl 2-methyl-2-(trifluoroacetamido)propanoate; (R)-2-(Trifluoroacetamido)-2-methylpropionic acid sec-butyl ester; (R)-α-Methyl-N-trifluoroacetylananine sec-butyl ester; (R)-N-TFA-α-methylalanine sec-butyl ester; (R)-N-Trifluoroacetyl-2-aminoisobutyric acid sec-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(Trifluoroacetylamino)Propionic Acid (R)-sec-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.