Description

2-Butenedioic Acid, 2,3-Bis[(Trimethylsilyl)Oxy]-, Bis(Trimethylsilyl) Ester, (Z)- is a highly functionalized, silyl-protected derivative of maleic acid. This compound is a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for sensitive or complex molecules. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Advanced Pharmaceutical Intermediates: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide and Nucleotide Chemistry: Used as a protecting group for carboxylic acid and hydroxyl functionalities during solid-phase and solution-phase synthesis.
• Polymer Science Research: Serves as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Material Science: Intermediate in the synthesis of advanced materials, including liquid crystals and organic semiconductors.
• Catalysis and Ligand Synthesis: Precursor for creating sophisticated chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Academic and Industrial R&D: A versatile reagent for methodological development and exploring new chemical transformations in organic chemistry.

Basic Information

Product Name	2-Butenedioic Acid, 2,3-Bis[(Trimethylsilyl)Oxy]-, Bis(Trimethylsilyl) Ester, (Z)-
CAS No.	55887-89-3
Molecular Formula	C16H36O6Si4
Molecular Weight	448.84 g/mol
Synonyms	(Z)-2,3-Bis(trimethylsiloxy)but-2-enedioic acid bis(trimethylsilyl) ester; Maleic Acid, Tetrakis(trimethylsilyl) Ester; Tetrakis(trimethylsilyl) Maleate; TMS-Maleate; Bis(trimethylsilyl) 2,3-bis(trimethylsiloxy)maleate; 2-Butenedioic acid, 2,3-bis[(trimethylsilyl)oxy]-, 1,4-bis(trimethylsilyl) ester, (Z)-; Maleic Acid Tetrakis-O-trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our production of this high-purity synthetic intermediate adheres to strict quality management protocols. Every batch is analyzed using advanced techniques including GC, HPLC, NMR, and FTIR to confirm identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) in a desiccated environment to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.