Description

n-(Trimethylsilyl)-2-[(Trimethylsilyl)oxy]benzamide is a specialized organosilicon compound featuring dual trimethylsilyl protecting groups. This chemical is a valuable reagent and synthetic intermediate, prized for its role in protecting sensitive functional groups and facilitating complex organic transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly where hydroxyl and amide groups require temporary protection.
• Agrochemical Synthesis: Serves as a key building block in the development of novel herbicides, fungicides, and insecticides.
• Peptide Chemistry: Employed as a protecting group agent for carboxylic acids and alcohols during solid-phase and solution-phase peptide synthesis.
• Material Science Research: Acts as a precursor or modifying agent in the development of silicon-containing polymers and advanced hybrid materials.
• Organic Synthesis Reagent: Facilitates various reactions, including silylation, and is used in the preparation of complex natural products and fine chemicals.
• Chemical Derivatization: Used in analytical chemistry to derivative compounds for Gas Chromatography-Mass Spectrometry (GC-MS) analysis, improving volatility and detection.

Basic Information

Product Name	n-(Trimethylsilyl)-2-[(Trimethylsilyl)oxy]benzamide
CAS No.	55887-58-6
Molecular Formula	C13H23NO2Si2
Molecular Weight	281.50 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]-N-(trimethylsilyl)benzamide; Benzamide, 2-[(trimethylsilyl)oxy]-N-(trimethylsilyl)-; N,O-Bis(trimethylsilyl)salicylamide; Salicylamide, N,O-bis(trimethylsilyl)-; Bis-TMS salicylamide; TMS-protected salicylamide; 2-Hydroxy-N-(trimethylsilyl)benzamide O-trimethylsilyl ether
EINECS	Contact for details

Quality Control

Our n-(Trimethylsilyl)-2-[(Trimethylsilyl)oxy]benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.