Description

2-Oxo-3-(Trimethylsilyl)Propionic Acid Trimethylsilyl Ester is a specialized organosilicon compound that serves as a versatile building block and protecting group reagent in advanced organic synthesis. Its dual silyl-protected structure offers unique reactivity and stability, making it a valuable intermediate for constructing complex molecules. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring keto-acid or protected carboxylate functionalities.
• Peptide Synthesis: Used as a protecting group reagent for carboxylic acids during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators that incorporate silicon into their molecular architecture.
• Material Science: Precursor for silicon-containing polymers and hybrid organic-inorganic materials with tailored thermal and mechanical properties.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel molecular libraries.
• Cross-Coupling Reactions: Serves as a substrate or reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	2-Oxo-3-(Trimethylsilyl)Propionic Acid Trimethylsilyl Ester
CAS No.	55887-51-9
Molecular Formula	C9H20O3Si2
Molecular Weight	232.42 g/mol
Synonyms	3-(Trimethylsilyl)pyruvic acid trimethylsilyl ester; Trimethylsilyl 3-(trimethylsilyl)pyruvate; 3-(Trimethylsilyl)-2-oxopropanoic acid trimethylsilyl ester; Pyruvic acid, 3-(trimethylsilyl)-, trimethylsilyl ester; TMS-Pyruvate TMS Ester; 2-Oxo-3-(trimethylsilyl)propanoic acid trimethylsilyl ester; (Trimethylsilyl)pyruvic acid TMS ester
EINECS	Contact for details

Quality Control

Our 2-Oxo-3-(Trimethylsilyl)Propionic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.