Description

2-[(Trimethylsilyl)Oxy]Valeric Acid Trimethylsilyl Ester is a specialized organosilicon compound that serves as a versatile protected intermediate in advanced organic synthesis. Its primary value lies in its dual silyl protection, which effectively masks reactive carboxylic acid and hydroxyl functionalities, enabling selective reactions in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials where precise molecular control is required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly where protection of sensitive functional groups is necessary.
• Peptide Synthesis: Used as a protected amino acid derivative or carboxyl component in solid-phase and solution-phase peptide coupling reactions.
• Agrochemical Production: Serves as an intermediate in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Employed in the synthesis of specialized monomers and silicone-based polymers with tailored properties.
• Organic Synthesis Reagent: Acts as a silylating agent and a protected form of valeric acid for introducing specific carbon chains in complex molecules.
• Flavor & Fragrance Chemistry: Used in the controlled synthesis of esters and other compounds for high-value aroma chemicals.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]Valeric Acid Trimethylsilyl Ester
CAS No.	55887-46-2
Molecular Formula	C11H26O3Si2
Molecular Weight	262.50 g/mol
Synonyms	2-(Trimethylsiloxy)pentanoic Acid Trimethylsilyl Ester; 2-(Trimethylsilyloxy)valeric Acid Trimethylsilyl Ester; Valeric Acid, 2-[(Trimethylsilyl)oxy]-, Trimethylsilyl Ester; 2-TMS-Oxyvaleric Acid TMS Ester; 2-(TMS-O)ValTMS; Pentanoic Acid, 2-[(Trimethylsilyl)oxy]-, Trimethylsilyl Ester; Bis(trimethylsilyl) 2-Hydroxyvalerate; 2-Hydroxyvaleric Acid Bis(trimethylsilyl) Ether
EINECS	Contact for details

Quality Control

Our production of 2-[(Trimethylsilyl)Oxy]Valeric Acid Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.