Description

5-Bromo-2-Ethoxypyridine is a versatile brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and ethoxy groups, which enable selective functionalization for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and photoactive compounds due to its modifiable aromatic structure.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and other complex systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	5-Bromo-2-Ethoxypyridine
CAS No.	55849-30-4
Molecular Formula	C7H8BrNO
Molecular Weight	202.05 g/mol
Synonyms	2-Ethoxy-5-bromopyridine; 5-Bromo-2-ethoxypyridine; 2-Bromo-5-ethoxypyridine (incorrect numbering); Pyridine, 5-bromo-2-ethoxy-; 55849-30-4; 5-Br-2-EtO-Py
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethoxypyridine is produced under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your precise research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.