Description

Androst-4-En-3-One, 17,19-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (1 7Beta)- is a high-purity, protected steroid derivative used as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of complex steroid-based molecules, where its trimethylsilyl (TMS) protecting groups offer precise control over chemical reactivity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the design and exploration of new therapeutic compounds targeting hormone receptors.
• Process Chemistry: Serves as a protected intermediate in the scale-up and optimization of synthetic routes for steroid manufacturing.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in academic and industrial labs studying steroid metabolism and enzyme interactions.

Basic Information

Product Name	Androst-4-En-3-One, 17,19-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (1 7Beta)-
CAS No.	55836-47-0
Molecular Formula	C₂₆H₄₇NO₃Si₂
Molecular Weight	477.84 g/mol
Synonyms	17β-Hydroxy-19-trimethylsilyloxyandrost-4-en-3-one o-methyloxime; 17β,19-Bis(trimethylsilyloxy)androst-4-en-3-one o-methyloxime; (17β)-17,19-Bis[(trimethylsilyl)oxy]androst-4-en-3-one O-methyloxime; Androst-4-ene-3-one, 17,19-bis[(trimethylsilyl)oxy]-, O-methyloxime, (17β)-; 55836-47-0; Steroid TMS derivative; Protected androstane derivative.
EINECS	Contact for details

Quality Control

Our Androst-4-En-3-One, 17,19-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (1 7Beta)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.