Description

19-[(Trimethylsilyl)Oxy]Androst-4-Ene-3,17-Dione Bis(o-Methyl Oxime) CAS NO 55836-46-9 is a high-purity, steroidal derivative featuring a trimethylsilyl-protected hydroxyl group and bis(o-methyl oxime) functionalization. This compound is a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and fine chemicals, offering precise control over molecular architecture. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and anticancer agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex, high-value specialty chemicals with specific stereochemistry.
• Biochemical Research: Employed as a probe or standard in biochemical assays and metabolic pathway studies involving steroid transformations.
• Process Chemistry: Utilized in process development and scale-up for the commercial manufacturing of steroid-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	19-[(Trimethylsilyl)Oxy]Androst-4-Ene-3,17-Dione Bis(o-Methyl Oxime)
CAS No.	55836-46-9
Molecular Formula	C24H40N2O3Si
Molecular Weight	432.68 g/mol
Synonyms	19-[(Trimethylsilyl)oxy]androst-4-ene-3,17-dione bis(O-methyloxime); 19-TMS-O-androst-4-ene-3,17-dione bis(O-methyloxime); Androst-4-ene-3,17-dione, 19-[(trimethylsilyl)oxy]-, bis(O-methyloxime); 19-Hydroxyandrost-4-ene-3,17-dione 19-TMS ether 3,17-bis(O-methyloxime); 3,17-Bis(methoxyimino)-19-[(trimethylsilyl)oxy]androst-4-ene
EINECS	Contact for details

Quality Control

Our 19-[(Trimethylsilyl)Oxy]Androst-4-Ene-3,17-Dione Bis(o-Methyl Oxime) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP pharmaceutical development and other high-standard industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.