Description

n-(2-Methyl-1-Oxo-2-Propenyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its dual functionality, offering a protected glycine moiety alongside a reactive acryloyl group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the development of novel peptide mimetics, active pharmaceutical ingredients (APIs), and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex peptide analogs and novel drug candidates, especially those requiring specific side-chain modifications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced activity profiles.
• Peptide Mimetic Synthesis: Facilitates the creation of peptidomimetics where the glycine backbone is incorporated into non-peptide structures to improve metabolic stability.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functionalized surfaces.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeled compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material for custom synthesis projects requiring protected amino acid chemistry.

Basic Information

Product Name	n-(2-Methyl-1-Oxo-2-Propenyl)Glycine Trimethylsilyl Ester
CAS No.	55836-40-3
Molecular Formula	C9H17NO3Si
Molecular Weight	215.32 g/mol
Synonyms	N-(2-Methyl-1-oxo-2-propen-1-yl)glycine trimethylsilyl ester; 2-[(Trimethylsilyl)oxycarbonylmethylamino]-2-methylprop-2-enoic acid methyl ester; Glycine, N-(2-methyl-1-oxo-2-propenyl)-, trimethylsilyl ester; Methacryloylglycine trimethylsilyl ester; TMS ester of N-methacryloylglycine
EINECS	Contact for details

Quality Control

Our n-(2-Methyl-1-Oxo-2-Propenyl)Glycine Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP and ISO standards ensures reliable material for your most demanding research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.