Description

2,4,5-Tris[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester is a highly functionalized, multi-silylated organic compound used as a key synthetic intermediate and protecting group reagent. Its value lies in providing a robust, multi-point silyl protection strategy for phenolic and carboxylic acid functionalities, enabling complex synthetic sequences in sensitive molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized building blocks for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a protected precursor in the multi-step synthesis of complex drug molecules, particularly those containing catechol or gallic acid-derived structures.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where phenolic protection is required.
• Advanced Material Monomer: Acts as a functional monomer or cross-linking agent in the synthesis of specialty silicones and silicon-containing polymers with unique thermal and surface properties.
• Organic Synthesis Reagent: Employed as a versatile silylating agent for the simultaneous protection of multiple hydroxyl and carboxyl groups under mild conditions.
• Chemical Research & Development: A critical tool in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.
• Fine Chemical Production: Integral to the manufacture of high-value, low-volume specialty chemicals, including dyes, pigments, and flavor/fragrance compounds.

Basic Information

Product Name	2,4,5-Tris[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester
CAS No.	55823-12-6
Molecular Formula	C20H38O5Si4
Molecular Weight	486.88 g/mol
Synonyms	2,4,5-Tris(trimethylsiloxy)benzeneacetic acid trimethylsilyl ester; Gallic acid tris(trimethylsilyl) ether trimethylsilyl ester; 3,4,5-Tris(trimethylsiloxy)benzenecarboxylic acid trimethylsilyl ester; TMS-protected gallic acid ester; Benzeneacetic acid, 2,4,5-tris[(trimethylsilyl)oxy]-, trimethylsilyl ester; Per(trimethylsilyl) gallate
EINECS	Contact for details

Quality Control

Our 2,4,5-Tris[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) documenting purity, identity, and relevant physical parameters is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.