Description

(3As,5S,6R,9E,14R,15R,15Ar)-2,3,3A,4,5,6,7,8,11,12,13,14,15,15A-Tetradecahydro-6,10,14-Trimethyl-3-Methylene-2-Oxo-5,15-Epoxycyclotetradeca[B]Furan-6-Ol Acetate is a high-purity, complex macrocyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block and intermediate for developing novel bioactive molecules. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to explore new molecular entities with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly for antibiotics and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel, high-specificity pesticides and herbicides due to its bioactive macrocyclic structure.
• Fine Chemical Synthesis: Acts as a sophisticated building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A critical compound for methodological studies in total synthesis, catalysis, and stereoselective reactions.
• Bioconjugate Chemistry: Potential use in designing targeted drug delivery systems or diagnostic agents by functionalizing its reactive sites.

Basic Information

Product Name	(3As,5S,6R,9E,14R,15R,15Ar)-2,3,3A,4,5,6,7,8,11,12,13,14,15,15A-Tetradecahydro-6,10,14-Trimethyl-3-Methylene-2-Oxo-5,15-Epoxycyclotetradeca[B]Furan-6-Ol Acetate
CAS No.	55822-20-3
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	6-O-Acetyl-9,10-didehydro-6-demethyl-8,9-dideoxygriseofulvin; 9,10-Didehydro-6-demethyl-8,9-dideoxygriseofulvin 6-acetate; A derivative of Griseofulvin; Macrocyclic furanone acetate; (5S,6R,14R)-6-(Acetyloxy)-5,15-epoxy-3-methylene-6,10,14-trimethyloxacyclotetradeca-9,12-diene-2,8-dione (alternative IUPAC); CAS 55822-20-3; Epoxycyclotetradecafuranol acetate
EINECS	Contact for details

Quality Control

Every batch of our (3As,5S,6R,9E,14R,15R,15Ar)-2,3,3A,4,5,6,7,8,11,12,13,14,15,15A-Tetradecahydro-6,10,14-Trimethyl-3-Methylene-2-Oxo-5,15-Epoxycyclotetradeca[B]Furan-6-Ol Acetate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.