Description

12β-Acetyloxy-11α-(3-Pyridylcarbonyloxy)-5α-Pregnane-3β,14β,20-Triol is a high-purity, synthetically derived pregnane steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. It is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate steroid hormone pathways, receptor binding, and metabolic interactions.
• Process Development: Serves as a critical material for scaling up synthetic routes and optimizing manufacturing processes in a GMP environment.
• Academic Research: Utilized by universities and research institutes for fundamental studies in organic chemistry, medicinal chemistry, and pharmacology.

Basic Information

Product Name	12β-Acetyloxy-11α-(3-Pyridylcarbonyloxy)-5α-Pregnane-3β,14β,20-Triol
CAS No.	55785-23-4
Molecular Formula	C₃₀H₄₁NO₇
Molecular Weight	527.65 g/mol
Synonyms	12β-Acetoxy-11α-(3-pyridylcarbonyloxy)-5α-pregnane-3β,14β,20-triol; 5α-Pregnane-3β,14β,20-triol, 12β-acetoxy-11α-(3-pyridinylcarbonyloxy)-; 12β-Acetoxy-11α-(nicotinoyloxy)-5α-pregnane-3β,14β,20-triol; 11α-(3-Pyridylcarbonyloxy)-12β-acetyloxy-5α-pregnane-3β,14β,20-triol; Pregnane Steroid Derivative 55785-23-4; 12β-Acetyloxy-11α-(3-pyridylcarbonyloxy)-5α-pregnane-3β,14β,20-triol
EINECS	Contact for details

Quality Control

Our 12β-Acetyloxy-11α-(3-Pyridylcarbonyloxy)-5α-Pregnane-3β,14β,20-Triol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.