Description

Ethyl 2,5-Dioxopyrrole-1-Carboxylate is a versatile heterocyclic building block and active pharmaceutical intermediate (API) of significant commercial importance. Its pyrrolidine-2,5-dione (succinimide) core structure makes it a critical precursor in the synthesis of various N-substituted pharmacologically active compounds. This high-purity intermediate is essential for research and manufacturing within the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of N-substituted succinimide derivatives, which are core structures in various active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that incorporate the pyrrolidine-2,5-dione moiety.
• Organic Synthesis Reagent: Serves as a protected glycine equivalent or a versatile electrophile in multi-step synthetic routes for complex organic molecules.
• Polymer Chemistry: Potential monomer or modifier in the development of specialty polymers with specific thermal or solubility properties.
• Material Science Research: Investigated for use in creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Can be utilized to introduce specific functional handles onto biomolecules for labeling or cross-linking applications.

Basic Information

Product Name	Ethyl 2,5-Dioxopyrrole-1-Carboxylate
CAS No.	55750-49-7
Molecular Formula	C7H7NO4
Molecular Weight	169.13 g/mol
Synonyms	1-(Ethoxycarbonyl)pyrrolidine-2,5-dione; Ethyl N-Carboxysuccinimide; Ethyl Succinimidyl Carbonate; 1-Carbethoxy-2,5-pyrrolidinedione; ESC; Succinimidyl Ethyl Carbonate; N-(Ethoxycarbonyl)succinimide; Ethyl 1-Carboxysuccinimidate
EINECS	Contact for details

Quality Control

Our Ethyl 2,5-Dioxopyrrole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.