Description

4-[(2R)-5β-(1,3-Benzodioxol-5-Yl)Tetrahydro-3β,4α-Dimethylfuran-2β-Yl]-2-Methoxyphenol Acetate is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex molecules, particularly within the pharmaceutical sector. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its specific structural framework into novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex natural product analogs or novel chemical entities.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Acts as an analytical standard for quality control and method development in regulatory filings.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, stereospecific crop protection agents.

Basic Information

Product Name	4-[(2R)-5β-(1,3-Benzodioxol-5-Yl)Tetrahydro-3β,4α-Dimethylfuran-2β-Yl]-2-Methoxyphenol Acetate
CAS No.	55730-99-9
Molecular Formula	C22H24O6
Molecular Weight	384.42 g/mol
Synonyms	(2R,3aS,4S,7aR)-4-(1,3-Benzodioxol-5-yl)-2-methoxyphenyl 3a,4-dimethylhexahydro-1-benzofuran-7-yl acetate; 4-[(2R,3aS,4S,7aR)-4-(1,3-Benzodioxol-5-yl)-3a,4-dimethylhexahydro-1-benzofuran-7-yl]-2-methoxyphenyl acetate; 2-Methoxy-4-[(2R,3aS,4S,7aR)-3a,4-dimethyl-4-(3,4-methylenedioxyphenyl)perhydro-1-benzofuran-7-yl]phenyl acetate; Acetate derivative of a tetrahydrobenzofuran-methoxyphenol conjugate.
EINECS	Contact for details

Quality Control

Our 4-[(2R)-5β-(1,3-Benzodioxol-5-Yl)Tetrahydro-3β,4α-Dimethylfuran-2β-Yl]-2-Methoxyphenol Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.