Description

O5'-Succinylvitamin B12 is a chemically modified derivative of cyanocobalamin (vitamin B12), where a succinyl group is attached to the ribose moiety. This modification enhances its stability and alters its solubility profile, making it a valuable intermediate for specialized pharmaceutical and nutraceutical synthesis. It is primarily utilized by manufacturers in the life sciences sector requiring high-purity, functionalized B12 compounds for advanced research and production.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel vitamin B12 analogs and prodrugs with targeted release properties.
• Biochemical Research: Used as a reference standard and reagent in metabolic pathway studies and enzymatic research involving cobalamin derivatives.
• Nutraceutical Formulation: An advanced ingredient for developing high-stability, specialized dietary supplements.
• Diagnostic Reagents: Employed in the development of immunoassays and diagnostic kits for vitamin B12 deficiency detection.
• Cell Culture Media: A specialized component in serum-free media formulations for sensitive cell lines.

Basic Information

Product Name	O5'-Succinylvitamin B12
CAS No.	55729-45-8
Molecular Formula	C63H88CoN14O17P
Molecular Weight	1402.3 g/mol
Synonyms	Succinylcobalamin; Vitamin B12 Succinate; Succinyl Vitamin B12; Cobinamide, Coalpha-[α-(5,6-dimethyl-1H-benzimidazol-1-yl)]-Cobeta-cyanide 5'--O-(3-carboxy-1-oxopropoxy) hydrogen phosphate (ester) inner salt; 5'-O-Succinylcyanocobalamin; Cyanocobalamin 5'-succinate; Coalpha-[α-(5,6-dimethyl-1H-benzimidazolyl)]-Cobeta-cyano-5'-O-succinylcobamide
EINECS	Contact for details

Quality Control

Our O5'-Succinylvitamin B12 is manufactured under strict quality management systems. Each batch is tested to ensure high chemical purity and identity, with specifications suitable for research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identification (IR/UV), and related substance profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is light-sensitive (store away from light). For long-term storage, consider keeping the container under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Dark red crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.