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2-Acetoxy-1-(Hydroxymethyl)Ethyl β-D-Glucopyranoside CAS NO 55729-18-5


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CAS No.:55729-18-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Acetoxy-1-(Hydroxymethyl)Ethyl β-D-Glucopyranoside is a specialized carbohydrate derivative, specifically a glycoside with an acetylated aglycone, offering unique chemical functionality for advanced synthesis. This compound matters as a versatile chiral building block and intermediate, enabling the development of complex molecules with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery, prodrug synthesis, and the creation of novel bioactive compounds.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for prodrug strategies and targeted drug delivery systems.
  • Glycoconjugate Synthesis: Used in the chemical and enzymatic synthesis of complex glycoconjugates, glycopeptides, and other biologically relevant carbohydrate structures for biochemical research.
  • Bioconjugation & Labeling: Acts as a functional handle for attaching sugars or other moieties to proteins, peptides, or small molecules, facilitating studies in chemical biology and diagnostics.
  • Fine Chemical Production: Employed as a high-value intermediate in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring specific sugar-based motifs.
  • Agrochemical Research: Investigated as a potential intermediate or active component in the development of new, more selective herbicides, insecticides, or plant growth regulators.
  • Cosmetic Ingredient Research: Explored for its potential use in advanced skincare formulations, where sugar derivatives are valued for their moisturizing and skin-conditioning properties.

Basic Information

Product Name 2-Acetoxy-1-(Hydroxymethyl)Ethyl β-D-Glucopyranoside
CAS No. 55729-18-5
Molecular Formula C12H20O9
Molecular Weight 308.28 g/mol
Synonyms 2-Acetoxy-1-(hydroxymethyl)ethyl β-D-glucopyranoside; 1,2-Isopropylidene-3-O-acetyl-α-D-glucofuranose (related intermediate); β-D-Glucopyranoside, 2-(acetyloxy)-1-(hydroxymethyl)ethyl; Acetylated glucose derivative; Glycosyl acetate derivative; (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-[(1S)-1,2-dihydroxyethyl]oxane-3,4,5-triol (systematic name); Contact for additional synonyms.
EINECS Contact for details

Quality Control

Our 2-Acetoxy-1-(Hydroxymethyl)Ethyl β-D-Glucopyranoside is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure the material meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Specific Rotation Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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