Description

1-Propanone, 1-[2,4-Bis[(Trimethylsilyl)Oxy]Phenyl]- is a specialized organosilicon-protected ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the dual trimethylsilyl (TMS) ether groups, which act as protecting groups for phenolic hydroxyls, enabling selective reactions in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, functionalized intermediates for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly where protection of phenolic OH groups is required.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that utilize phenolic ketone backbones.
• Organic Synthesis Reagent: Serves as a protected precursor for generating other functionalized aromatic ketones and chalcone derivatives in academic and industrial R&D.
• Material Science Research: Potential intermediate in the development of organic semiconductors, ligands for catalysts, and photoactive polymers.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1-Propanone, 1-[2,4-Bis[(Trimethylsilyl)Oxy]Phenyl]-
CAS No.	55724-93-1
Molecular Formula	C15H26O3Si2
Molecular Weight	310.54 g/mol
Synonyms	1-[2,4-Bis(trimethylsiloxy)phenyl]-1-propanone; 2',4'-Bis(trimethylsilyloxy)propiophenone; 1-Propanone,1-[2,4-bis[(trimethylsilyl)oxy]phenyl]-; Propiophenone, 2',4'-bis(trimethylsiloxy)-; 2,4-Bis-O-(trimethylsilyl)propiophenone; TMS-protected 2',4'-Dihydroxypropiophenone
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 1-[2,4-Bis[(Trimethylsilyl)Oxy]Phenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC, and NMR for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.