Description

2-Bromo-5-Hydroxypyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for constructing complex molecules with high precision and functionality. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	2-Bromo-5-Hydroxypyridine
CAS No.	55717-45-8
Molecular Formula	C5H4BrNO
Molecular Weight	173.99 g/mol
Synonyms	5-Hydroxy-2-bromopyridine; 2-Bromo-5-pyridinol; 5-Bromo-2-hydroxypyridine; 2-Bromo-5-pyridinone (tautomer); 2-Bromopyridin-5-ol; 5-Bromo-2(1H)-pyridinone; 2-Bromo-5-hydroxypyridine; Bromohydroxypyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Hydroxypyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.