Description

T-Butyl 3-Chloropropanoate is a versatile organic ester building block, specifically the tert-butyl ester of 3-chloropropanoic acid. This compound is valued for its role as a protected carboxylic acid intermediate in multi-step organic synthesis, where the tert-butyl group offers stability under various reaction conditions and can be selectively cleaved. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), where it serves as a protected carboxylic acid moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require a chloropropanoate ester backbone.
• Peptide Mimetics & Prodrug Development: Employed in medicinal chemistry for creating peptide analogs and designing prodrugs due to its hydrolyzable ester linkage.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialty polymers, coatings, and functional materials.
• Organic Synthesis Reagent: Utilized in various name reactions and transformations, such as alkylations and Michael additions, to introduce the 3-chloropropionate group.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.

Basic Information

Product Name	T-Butyl 3-Chloropropanoate
CAS No.	55710-80-0
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	tert-Butyl 3-chloropropionate; 3-Chloropropionic Acid tert-Butyl Ester; tert-Butyl β-chloropropionate; Propanoic acid, 3-chloro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-chloropropanoate; 3-Chloropropanoic acid tert-butyl ester; t-Butyl 3-chloropropionate
EINECS	Contact for details

Quality Control

Our T-Butyl 3-Chloropropanoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Refractive Index	1.425 - 1.435
Density	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.