Description

2-Methyl-3-[2-Methyl-4-[(Trimethylsilyl)Oxy]Phenyl]Quinazolin-4(3H)-One is a specialized quinazolinone derivative featuring a trimethylsilyl-protected phenolic group, making it a valuable synthetic intermediate in advanced organic chemistry. This compound is crucial for research and development in pharmaceutical chemistry, particularly in the synthesis of complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core structure.
• Organic Synthesis Reagent: Acts as a protected phenol derivative for constructing complex molecular architectures in academic and industrial research laboratories.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers due to its fused aromatic system.
• Chemical Biology Probe Development: Employed in the creation of tool compounds for studying biological processes and target validation.

Basic Information

Product Name	2-Methyl-3-[2-Methyl-4-[(Trimethylsilyl)Oxy]Phenyl]Quinazolin-4(3H)-One
CAS No.	55683-27-7
Molecular Formula	C21H24N2O2Si
Molecular Weight	364.52 g/mol
Synonyms	4(3H)-Quinazolinone, 2-methyl-3-[2-methyl-4-[(trimethylsilyl)oxy]phenyl]-; 3-(2-Methyl-4-(trimethylsilyloxy)phenyl)-2-methylquinazolin-4(3H)-one; 2-Methyl-3-(2-methyl-4-(trimethylsilyloxy)phenyl)-4(3H)-quinazolinone; TMS-protected Quinazolinone Derivative; 4(3H)-Quinazolinone, 2-methyl-3-[2-methyl-4-[(trimethylsilyl)oxy]phenyl]- (9CI)
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-3-[2-Methyl-4-[(Trimethylsilyl)Oxy]Phenyl]Quinazolin-4(3H)-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.