Description

Difluoro(4-Methylphenyl)Methyl Isocyanate is a specialized aromatic isocyanate derivative featuring a difluoromethyl substituent. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce both the isocyanate and fluorinated aromatic moieties into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active molecules, particularly for creating urea and carbamate derivatives with potential therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the fluorinated aromatic structure can enhance metabolic stability and bioavailability.
• Polymer Science: Serves as a monomer or cross-linking agent in the production of specialized polyurethanes and polyurea coatings with unique chemical resistance properties.
• Material Science Research: Employed in the creation of advanced functional materials, such as liquid crystals or organic semiconductors, where precise molecular architecture is required.
• Chemical Biology Probes: Acts as a reagent for modifying proteins or other biomolecules to study biological pathways and interactions.

Basic Information

Product Name	Difluoro(4-Methylphenyl)Methyl Isocyanate
CAS No.	55682-93-4
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	1-Isocyanato-1-(4-methylphenyl)-2,2-difluoroethane; α,α-Difluoro-4-methylbenzyl Isocyanate; (4-Methylphenyl)difluoromethyl Isocyanate; 2,2-Difluoro-1-isocyanato-1-(p-tolyl)ethane; p-Tolyldifluoromethyl Isocyanate; Difluoro(p-tolyl)methyl Isocyanate
EINECS	Contact for details

Quality Control

Our Difluoro(4-Methylphenyl)Methyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.