Description

n-[4-(Trimethylsiloxy)Benzoyl]Glycine Methyl Ester is a specialized organosilicon derivative of glycine, serving as a key synthetic intermediate. This compound is valued for its unique chemical structure, which combines a silyl-protected phenolic group with an amino acid ester, enabling precise modifications in complex organic syntheses. It is primarily sought by research and development chemists in the pharmaceutical and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring silyl-protected phenolic functionalities.
• Peptide Mimetics Research: Serves as a building block for creating modified peptide analogs and peptidomimetics in medicinal chemistry.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the 4-(trimethylsiloxy)benzoyl moiety into target molecules.
• Material Science Precursor: Potential precursor in the development of specialty polymers or surface-modifying agents.
• Chemical Biology Probes: Utilized in the design and synthesis of probes for studying biological systems and enzyme activity.

Basic Information

Product Name	n-[4-(Trimethylsiloxy)Benzoyl]Glycine Methyl Ester
CAS No.	55638-48-7
Molecular Formula	C13H19NO4Si
Molecular Weight	281.38 g/mol
Synonyms	Glycine, N-[4-(trimethylsilyloxy)benzoyl]-, methyl ester; Methyl N-[4-(trimethylsilyloxy)benzoyl]glycinate; 4-(Trimethylsiloxy)benzoic acid glycine methyl ester amide; Methyl 2-[[4-(trimethylsilyloxy)benzoyl]amino]acetate; NSC 339063; p-(Trimethylsiloxy)hippuric acid methyl ester
EINECS	Contact for details

Quality Control

Our n-[4-(Trimethylsiloxy)Benzoyl]Glycine Methyl Ester is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.