Description

3-[(2S)-1-Trimethylsilyl-2-Pyrrolidinyl]Pyridine is a high-purity, chiral organosilicon compound that serves as a sophisticated building block and ligand in advanced synthetic chemistry. Its value lies in its ability to impart stereochemical control and silicon-based functionality in complex molecular assemblies, which is critical for developing novel materials and active pharmaceutical ingredients. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-quality intermediates for asymmetric synthesis and catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Asymmetric Catalysis Ligand: Used as a precursor or direct ligand in transition metal catalysis for enantioselective C-C and C-N bond-forming reactions.
• Agrochemical Research: Employed in the development of novel, stereochemically-defined active ingredients for crop protection.
• Material Science: Serves as a functional monomer or cross-linking agent in the development of advanced silicon-containing polymers and resins.
• Academic & R&D: A valuable tool for methodological development in organic synthesis and stereochemistry research at universities and corporate R&D centers.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-[(2S)-1-Trimethylsilyl-2-Pyrrolidinyl]Pyridine
CAS No.	55638-44-3
Molecular Formula	C12H20N2Si
Molecular Weight	220.39 g/mol
Synonyms	(S)-1-Trimethylsilyl-2-(3-pyridyl)pyrrolidine; (S)-1-(Trimethylsilyl)-2-(3-pyridinyl)pyrrolidine; (2S)-1-(Trimethylsilyl)-2-(3-pyridinyl)pyrrolidine; 3-[(2S)-1-(Trimethylsilyl)-2-pyrrolidinyl]pyridine; 3-[(2S)-1-(TMS)-2-pyrrolidinyl]pyridine; (S)-2-(3-Pyridyl)-1-(trimethylsilyl)pyrrolidine; Pyrrolidine, 1-(trimethylsilyl)-2-(3-pyridinyl)-, (2S)-
EINECS	Contact for details

Quality Control

Every batch of 3-[(2S)-1-Trimethylsilyl-2-Pyrrolidinyl]Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards. Our quality commitment includes providing full traceability and supporting documentation. A detailed Certificate of Analysis (COA) is available for each lot, confirming specifications for assay, chiral purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.