Description

(2R)-2,3,4,4Aβ,6,7,8,8Aβ-Octahydro-4-Acetyl-2,5α-Methano-5H-Pyrido[3,2-B]-1,4-Oxazine is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in complex organic syntheses. Its unique fused ring structure and specific stereochemistry make it an invaluable building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create molecules with precise three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used as a precursor in the development of novel, stereoselective pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new cyclization and functionalization reactions.
• Fine Chemical Production: Employed in the manufacture of high-value, specialty chemicals requiring specific stereochemical configurations.

Basic Information

Product Name	(2R)-2,3,4,4Aβ,6,7,8,8Aβ-Octahydro-4-Acetyl-2,5α-Methano-5H-Pyrido[3,2-B]-1,4-Oxazine
CAS No.	55623-00-2
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	(2R)-4-Acetyl-2,5α-methano-2,3,4,4aβ,6,7,8,8aβ-octahydro-5H-pyrido[3,2-b][1,4]oxazine; 4-Acetyl-2,5α-methano-2,3,4,4aβ,6,7,8,8aβ-octahydro-5H-pyrido[3,2-b][1,4]oxazine, (2R)-; (2R)-4-Acetyl-2,5-methano-2,3,4,4a,6,7,8,8a-octahydro-5H-pyrido[3,2-b][1,4]oxazine; Pyrido[3,2-b][1,4]oxazine intermediate; Chiral octahydro-pyridoxazine derivative
EINECS	Contact for details

Quality Control

Our (2R)-2,3,4,4Aβ,6,7,8,8Aβ-Octahydro-4-Acetyl-2,5α-Methano-5H-Pyrido[3,2-B]-1,4-Oxazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.