Description

1,7-Bis(Trimethylsilyl)Hypoxanthine is a high-purity, silylated derivative of the nucleobase hypoxanthine, designed for advanced synthetic applications. This compound is valued for its role as a key protected intermediate in the synthesis of modified nucleosides, nucleotides, and oligonucleotides, where it facilitates precise chemical transformations. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require reliable, high-quality building blocks for their complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial protected building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA sequences for research, diagnostics, and therapeutic applications (e.g., antisense oligonucleotides).
• Agrochemical Research: Serves as an intermediate in developing novel pesticides or plant growth regulators that target nucleic acid metabolism.
• Biochemical Research: Employed in studies of enzyme mechanisms, nucleic acid chemistry, and as a precursor for labeled compounds.
• Material Science: Potential use in creating functionalized surfaces or polymers with nucleobase recognition properties.

Basic Information

Product Name	1,7-Bis(Trimethylsilyl)Hypoxanthine
CAS No.	55622-58-7
Molecular Formula	C₁₁H₂₀N₄OSi₂
Molecular Weight	268.48 g/mol
Synonyms	1,7-Bis(trimethylsilyl)-1H-purin-6(7H)-one; Hypoxanthine, 1,7-bis(trimethylsilyl)-; 1,7-Bis-TMS-hypoxanthine; N1,N7-Bis(trimethylsilyl)hypoxanthine; 1,7-BTMS-Hypoxanthine; 1,7-Bis(trimethylsilyl)-6-hydroxypurine
EINECS	Contact for details

Quality Control

Every batch of 1,7-Bis(Trimethylsilyl)Hypoxanthine is manufactured and tested under strict quality management protocols to ensure consistency and reliability. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for high-purity intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.