Description

n-[4-[(Trimethylsilyl)Oxy]Benzoyl]Glycine Trimethylsilyl Ester is a high-purity, organosilicon-protected derivative of a glycine-benzoic acid conjugate, designed for advanced synthetic applications. This compound is valued for its role as a key synthetic intermediate and protecting group reagent, offering enhanced stability and reactivity in sensitive chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a protected building block in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Mimetic Synthesis: Used in the preparation of modified amino acid derivatives and peptide analogs for medicinal chemistry research.
• Agrochemical Research: Acts as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Proteomics: Can be employed as a specialty reagent or linker in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Material Science: Utilized in the synthesis of functionalized organic molecules for advanced materials, such as liquid crystals or organic semiconductors.
• Academic & Contract Research: A valuable tool for methodological development in organic synthesis and catalysis studies within R&D laboratories.

Basic Information

Product Name	n-[4-[(Trimethylsilyl)Oxy]Benzoyl]Glycine Trimethylsilyl Ester
CAS No.	55622-53-2
Molecular Formula	C15H25NO4Si2
Molecular Weight	339.54 g/mol
Synonyms	Glycine, N-[4-[(trimethylsilyl)oxy]benzoyl]-, trimethylsilyl ester; 4-(Trimethylsiloxy)benzoylglycine Trimethylsilyl Ester; N-(4-Trimethylsiloxybenzoyl)glycine Trimethylsilyl Ester; TMS-protected 4-Hydroxybenzoylglycine; Silylated Benzoylglycine Derivative; 55622-53-2; Benzoylglycine TMS Ester
EINECS	Contact for details

Quality Control

Our n-[4-[(Trimethylsilyl)Oxy]Benzoyl]Glycine Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.