Description

[(4α,14-Dimethyl-5α-Ergosta-8,24(28)-Dien-3β-Yl)Oxy]Trimethylsilane is a high-purity, organosilicon-protected sterol derivative, a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role in facilitating complex synthetic pathways where the protection of the 3β-hydroxy group is required, enabling selective reactions in the synthesis of novel steroidal compounds. It is primarily needed by research institutions and pharmaceutical development companies working on sterol-based drug discovery, chemical biology probes, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key protected intermediate in the multi-step synthesis of novel steroidal drugs and bioactive molecules.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic routes to functionalized ergostane and related sterol skeletons.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Bioconjugation Chemistry: Potential use in creating sterol-conjugated molecules for targeted delivery or labeling applications, leveraging the silyl ether's stability and later deprotection.
• Material Science Precursor: Can be investigated as a building block for sterol-containing hybrid organic-silicon materials.

Basic Information

Item	Details
Product Name	[(4α,14-Dimethyl-5α-Ergosta-8,24(28)-Dien-3β-Yl)Oxy]Trimethylsilane
CAS No.	55622-52-1
Molecular Formula	C33H58OSi
Molecular Weight	498.90 g/mol
Synonyms	3β-[(Trimethylsilyl)oxy]-4α,14-dimethyl-5α-ergosta-8,24(28)-diene; Ergosta-8,24(28)-dien-3-ol, 4,14-dimethyl-, 3-(trimethylsilyl) ether, (3β,4α,5α)-; 4α,14-Dimethyl-5α-ergosta-8,24(28)-dien-3β-yloxytrimethylsilane; (3β,4α,5α)-4,14-Dimethylergosta-8,24(28)-dien-3-yl trimethylsilyl ether; TMS-protected 4α,14-dimethyl-5α-ergosta-8,24(28)-dien-3β-ol; Trimethylsilyl ether of 4,14-dimethylergosta-8,24(28)-dien-3β-ol
EINECS	Contact for details

Quality Control

Our [(4α,14-Dimethyl-5α-Ergosta-8,24(28)-Dien-3β-Yl)Oxy]Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.