Description

5-Methoxy-1-(Trimethylsilyl)-1H-Indole-3-Acetic Acid Methyl Ester is a sophisticated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a protected indole nitrogen and a functionalized acetic acid side chain, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the synthesis of complex bioactive molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of specialty polymers and advanced organic electronic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in heterocyclic and organosilicon chemistry.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	5-Methoxy-1-(Trimethylsilyl)-1H-Indole-3-Acetic Acid Methyl Ester
CAS No.	55591-01-0
Molecular Formula	C15H21NO3Si
Molecular Weight	291.42 g/mol
Synonyms	Methyl 5-Methoxy-1-(trimethylsilyl)-1H-indole-3-acetate; 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, methyl ester; 5-Methoxy-1-trimethylsilylindole-3-acetic acid methyl ester; Methyl (5-methoxy-1-trimethylsilylindol-3-yl)acetate; 3-(Methoxycarbonylmethyl)-5-methoxy-1-trimethylsilylindole; 55591-01-0; 5-Methoxy-1-TMS-indole-3-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-1-(Trimethylsilyl)-1H-Indole-3-Acetic Acid Methyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with each shipment and are available upon request to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.