Description

n-(2-Methyl-1-Oxo-2-Propenyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in providing a dual-protected glycine moiety, offering enhanced stability and reactivity control during complex peptide and heterocycle formation. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, protected intermediates for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid motifs.
• Peptide Chemistry: Facilitates solid-phase and solution-phase peptide synthesis (SPPS) by protecting the amino and carboxyl groups of glycine, preventing unwanted side reactions.
• Heterocyclic Compound Production: Serves as a precursor in the synthesis of complex nitrogen-containing heterocycles, which are core structures in many bioactive molecules.
• Material Science Research: Employed in the development of functionalized polymers and silicon-containing hybrid materials.
• Chemical Biology Probes: Used to create labeled or modified amino acids for studying protein function and interactions.

Basic Information

Product Name	n-(2-Methyl-1-Oxo-2-Propenyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester
CAS No.	55557-27-2
Molecular Formula	C12H23NO3Si2
Molecular Weight	285.49 g/mol
Synonyms	N-(2-Methyl-1-oxo-2-propen-1-yl)-N-(trimethylsilyl)glycine trimethylsilyl ester; N-(Trimethylsilyl)-N-(methacryloyl)glycine trimethylsilyl ester; Methacryloylglycine bis(trimethylsilyl) ester; Bis(trimethylsilyl) N-methacryloylglycinate; Glycine, N-(2-methyl-1-oxo-2-propenyl)-N-(trimethylsilyl)-, trimethylsilyl ester; N-Methacryloyl-N-trimethylsilylglycine trimethylsilyl ester; Protected Methacryloylglycine
EINECS	Contact for details

Quality Control

Our n-(2-Methyl-1-Oxo-2-Propenyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.