Description

2,2'-Oxybis(Acetic Acid Trimethylsilyl) Ester is a specialized organosilicon compound used as a versatile silylating agent and protecting group in advanced organic synthesis. Its core value lies in its ability to efficiently protect hydroxyl and carboxyl groups, facilitating complex multi-step reactions with high selectivity and yield. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance intermediates for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key protecting group reagent in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides where selective protection of functional groups is required.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialty silicones and silicon-containing polymers with tailored properties.
• Analytical Chemistry: Utilized as a derivatization agent in Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS) for the analysis of polar compounds like acids and alcohols.
• Peptide & Carbohydrate Chemistry: Provides protection for sensitive functional groups during the synthesis of peptides, oligonucleotides, and complex sugars.
• Fine Chemical Manufacturing: Serves as a crucial reagent in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	2,2'-Oxybis(Acetic Acid Trimethylsilyl) Ester
CAS No.	55557-25-0
Molecular Formula	C10H24O5Si2
Molecular Weight	280.47 g/mol
Synonyms	Bis(trimethylsilyl) Diglycolate; Diglycolic Acid Bis(trimethylsilyl) Ester; 2,2'-Oxybis[acetic acid bis(trimethylsilyl) ester]; Oxybis(acetic acid) bis(trimethylsilyl) ester; TMS Diglycolate; Bis(TMS) Diglycolate; Diglycolic Acid Bis(TMS) Ester; 2,2'-Oxybisacetic Acid Bis(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our 2,2'-Oxybis(Acetic Acid Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.