Description

2-Methyl-3-Oxo-3-[[2-Oxo-2-(Trimethylsiloxy)Ethyl](Trimethylsilyl)Amino]Propionic Acid is a specialized organosilicon-protected amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a protected intermediate, enabling the controlled construction of complex molecules where standard amino acid reactivity must be temporarily masked. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of novel peptides, active pharmaceutical ingredients (APIs), and other high-value synthetic targets.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptide-based drugs and novel active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Fine Chemical Production: Serves as a crucial intermediate in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and bioactive compounds.
• Organosilicon Chemistry: Utilized in studies and applications involving silyl-protecting groups for carboxylic acids and amines.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	2-Methyl-3-Oxo-3-[[2-Oxo-2-(Trimethylsiloxy)Ethyl](Trimethylsilyl)Amino]Propionic Acid
CAS No.	55557-20-5
Molecular Formula	C13H27NO5Si2
Molecular Weight	333.53 g/mol
Synonyms	3-[[2-Oxo-2-(Trimethylsiloxy)Ethyl](Trimethylsilyl)Amino]-2-Methyl-3-Oxopropanoic Acid; N-[2-Oxo-2-(Trimethylsiloxy)Ethyl]-N-(Trimethylsilyl)-2-Methylmalonamic Acid; 2-Methylmalonamic Acid N-[2-Oxo-2-(Trimethylsiloxy)Ethyl]-N-(Trimethylsilyl)-; Protected 2-Methylmalonamic Acid Derivative; TMS-Protected Amino Acid Ester; Bis(trimethylsilyl) Protected Amino Acid Intermediate
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-Oxo-3-[[2-Oxo-2-(Trimethylsiloxy)Ethyl](Trimethylsilyl)Amino]Propionic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.