Description

3-(5-Ethylhexahydro-1,3-Dimethyl-2,4,6-Trioxopyrimidin-5-Yl)-1-Methylbutyl 2-O,3-O,4-o-Tris(Trimethylsilyl)-6-o-Methyl-D-Glucopyranosiduronic Acid is a sophisticated, high-purity chemical intermediate featuring a protected glucuronic acid moiety linked to a barbiturate-derived structure. This compound is critical for advanced synthetic chemistry, particularly in the development of novel pharmaceuticals and bioactive molecules where precise glycosylation and controlled release are required. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new therapeutic agents or complex molecular conjugates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those requiring glucuronidation for targeted delivery or prodrug strategies.
• Glycoconjugate Synthesis: Used in the research and development of glycoproteins, glycolipids, and other biologically active glycosylated compounds.
• Prodrug Development: The protected glucuronic acid moiety makes it valuable for designing prodrugs that are activated by specific enzymatic cleavage in vivo.
• Chemical Biology Research: Employed as a tool compound for studying enzyme mechanisms, metabolic pathways, and glycosylation processes.
• Fine Chemical Synthesis: Serves as a specialized building block for creating high-value, complex molecules in custom synthesis and contract manufacturing.
• Analytical Reference Standard: Used as a high-purity standard in analytical methods (HPLC, LC-MS) for quality control and metabolic studies.

Basic Information

Product Name	3-(5-Ethylhexahydro-1,3-Dimethyl-2,4,6-Trioxopyrimidin-5-Yl)-1-Methylbutyl 2-O,3-O,4-o-Tris(Trimethylsilyl)-6-o-Methyl-D-Glucopyranosiduronic Acid
CAS No.	55556-79-1
Molecular Formula	C30H56N2O11Si3
Molecular Weight	713.1 g/mol
Synonyms	1-Methylbutyl 2,3,4-Tris-O-(trimethylsilyl)-6-O-methyl-β-D-glucopyranosiduronic Acid 5-[1-(5-Ethyl-1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)ethyl] Ester; TMS-Protected Glucuronic Acid-Barbiturate Conjugate; 6-O-Methyl-D-glucopyranosiduronic Acid, 2,3,4-tris-O-(trimethylsilyl)-, 5-[1-(5-ethyl-1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)ethyl] 1-methylbutyl ester; Barbiturate-Glucuronide Intermediate; CAS 55556-79-1
EINECS	Contact for details

Quality Control

Our 3-(5-Ethylhexahydro-1,3-Dimethyl-2,4,6-Trioxopyrimidin-5-Yl)-1-Methylbutyl 2-O,3-O,4-o-Tris(Trimethylsilyl)-6-o-Methyl-D-Glucopyranosiduronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.