Description

6-o-[Bis(Trimethylsiloxy)Phosphinyl]-3-O,4-O,5-o-Tris(Trimethylsilyl)-2-Deoxy-D-Arabino-Hexonic Acid Trimethylsilyl Ester is a highly specialized, fully protected carbohydrate derivative, primarily used as a critical synthetic intermediate. Its value lies in its role as a key building block for the controlled synthesis of complex oligosaccharides, glycoconjugates, and nucleoside analogs. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the fields of antiviral and anticancer drug discovery, as well as in advanced carbohydrate chemistry research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogs for antiviral and anticancer therapeutics.
• Oligosaccharide Synthesis: Serves as a protected glycosyl donor or acceptor for the stepwise construction of complex carbohydrate chains.
• Glycoconjugate Development: Used in the preparation of glycopeptides, glycolipids, and other biologically active molecules for drug targeting and vaccine development.
• Chemical Biology Probes: Enables the creation of labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
• Process Chemistry: Employed in route development and scale-up for the production of active pharmaceutical ingredients (APIs) with carbohydrate motifs.
• Academic & Industrial R&D: A valuable reagent for methodology development in synthetic organic and medicinal chemistry laboratories.

Basic Information

Item	Details
Product Name	6-o-[Bis(Trimethylsiloxy)Phosphinyl]-3-O,4-O,5-o-Tris(Trimethylsilyl)-2-Deoxy-D-Arabino-Hexonic Acid Trimethylsilyl Ester
CAS No.	55538-92-6
Molecular Formula	C24H61NO9PSi6
Molecular Weight	708.31 g/mol
Synonyms	2-Deoxy-D-arabino-hexonic acid, 6-[bis(trimethylsiloxy)phosphinyl]-3,4,5-tris-O-(trimethylsilyl)-, trimethylsilyl ester; 2-Deoxy-6-O-(phosphono)-D-glucose hexakis(trimethylsilyl) ester; Fully TMS-protected 2-deoxyglucose-6-phosphate derivative; Hexakis(trimethylsilyl) 2-deoxy-D-glucose-6-phosphate; TMS-2-deoxyglucose-6-phosphate
EINECS	Contact for details

Quality Control

Our production of this high-purity synthetic intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research and development applications. Quality is verified through advanced analytical techniques including NMR (¹H, ¹³C, ³¹P), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.