Description

Hexitol, Hexakis(Trifluoroacetate) is a fully esterified derivative of a hexitol sugar alcohol, where all six hydroxyl groups are substituted with trifluoroacetyl groups. This chemical modification imparts unique properties, including enhanced solubility in organic solvents and altered reactivity, making it a valuable synthetic intermediate and protecting group reagent. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for specialized synthesis and derivatization processes. The compound is supplied with the CAS registry number 55538-86-8.

Application

• Pharmaceutical Intermediate: Serves as a key building block or protecting group agent in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its trifluoroacetate groups can influence biological activity.
• Polymer Science: Acts as a monomer or cross-linking agent for creating specialty polymers with specific thermal or solubility characteristics.
• Chemical Derivatization: Employed in analytical chemistry to derivative sugars or polyols for improved detection and separation in techniques like Gas Chromatography (GC) or Mass Spectrometry (MS).
• Material Science Research: Investigated for use in surface modification, creating hydrophobic coatings, or as a precursor for advanced organic frameworks.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing trifluoroacetate esters in complex organic transformations.

Basic Information

Item	Detail
Product Name	Hexitol, Hexakis(Trifluoroacetate)
CAS No.	55538-86-8
Molecular Formula	C18H12F18O12 (Exact formula depends on the parent hexitol isomer; contact for details)
Molecular Weight	Contact for details
Synonyms	Hexitol Hexa(trifluoroacetate); Hexitol Per(trifluoroacetate); 1,2,3,4,5,6-Hexakis-O-(trifluoroacetyl)hexitol; Hexitol Trifluoroacetate Ester; Polyol Trifluoroacetate; Sugar Alcohol Trifluoroacetate Derivative; TFA Ester of Hexitol
EINECS	Contact for details

Quality Control

Every batch of Hexitol, Hexakis(Trifluoroacetate) is produced and tested under strict quality management protocols to ensure consistency and reliability for research and industrial use. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. While specific pharmacopeial standards (USP/EP) may not apply, our in-house specifications are designed to meet the rigorous demands of chemical synthesis. Please contact us to discuss custom purity grades or specific analytical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.