Description

D-Fructose, 1,3,4,5-Tetrakis-o-(Trimethylsilyl)-, 6-[Bis(Trimethylsilyl) Phosphate] is a highly functionalized, silyl-protected fructose derivative, serving as a critical advanced intermediate in organic synthesis. This compound is valued for its role in introducing phosphorylated sugar moieties and for its utility in protecting group chemistry, enabling complex carbohydrate and nucleoside analog synthesis. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require precise, high-purity building blocks for sophisticated molecular construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs, prodrugs, and carbohydrate-based therapeutics.
• Agrochemical Research: Used in developing advanced crop protection agents and plant growth regulators with specific bioactive sugar-phosphate motifs.
• Glycochemistry & Glycobiology: Serves as a protected and activated precursor for constructing complex oligosaccharides and glycoconjugates.
• Chemical Biology Probes: Utilized in creating labeled or modified sugar-phosphates for studying enzymatic pathways and metabolic processes.
• Process Development: Acts as a standardized intermediate for scaling up the production of specialty fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis.

Basic Information

Item	Details
Product Name	D-Fructose, 1,3,4,5-Tetrakis-o-(Trimethylsilyl)-, 6-[Bis(Trimethylsilyl) Phosphate]
CAS No.	55530-83-1
Molecular Formula	C24H61O9PSi6
Molecular Weight	Approx. 677.3 g/mol
Synonyms	1,3,4,5-Tetra-O-(trimethylsilyl)-D-fructopyranose 6-(bis(trimethylsilyl) phosphate); D-Fructose, 1,3,4,5-tetrakis-O-(trimethylsilyl)-, 6-(bis(trimethylsilyl) phosphate); Fructose-1,3,4,5-tetrakis(trimethylsilyl) 6-bis(trimethylsilyl) phosphate; Per-TMS Fructose Phosphate; TMS-Protected Fructose Phosphate Ester; Hexakis(trimethylsilyl) D-fructopyranose phosphate
EINECS	Contact for details

Quality Control

Every batch of our D-Fructose, 1,3,4,5-Tetrakis-o-(Trimethylsilyl)-, 6-[Bis(Trimethylsilyl) Phosphate] is produced and tested under strict quality management protocols to ensure high purity, consistency, and reliability for your critical research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and identity confirmation. Our quality systems are designed to support cGMP and ISO-aligned manufacturing for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/NMR)	≥ 95%
Purity (HPLC)	≥ 97% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.