Description

3-Methoxy-α-[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester is a key silylated intermediate and protecting group reagent in advanced organic synthesis. Its primary value lies in enabling complex multi-step reactions, particularly in the synthesis of pharmaceuticals and fine chemicals, by providing stability and selectivity for sensitive functional groups. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing protected carboxylic acid or phenol moieties.
• Peptide & Carbohydrate Chemistry: Used as a protecting group reagent for hydroxyl and carboxyl functions during complex oligomer synthesis.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the development of specialty polymers and advanced organic electronic materials.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in organic chemistry laboratories.
• Fine Chemical Production: Used in the manufacture of complex fragrance compounds, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	3-Methoxy-α-[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester
CAS No.	55530-67-1
Molecular Formula	C15H26O4Si2
Molecular Weight	326.54 g/mol
Synonyms	(3-Methoxyphenyl)(trimethylsilyloxy)acetic acid trimethylsilyl ester; Trimethylsilyl 2-(trimethylsilyloxy)-2-(3-methoxyphenyl)acetate; 2-(3-Methoxyphenyl)-2-[(trimethylsilyl)oxy]acetic acid trimethylsilyl ester; α-(Trimethylsiloxy)-3-methoxybenzeneacetic acid trimethylsilyl ester; 3-Methoxy-α-(trimethylsiloxy)benzeneacetic acid TMS ester; TMS ester of 3-methoxy-α-(trimethylsiloxy)phenylacetic acid; Silated 3-methoxymandelic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Methoxy-α-[(Trimethylsilyl)Oxy]Benzeneacetic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to prevent hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.