Description

2-(Trimethylsilyl)-2-(Trimethylsiloxy)Malonic Acid Bis(Trimethylsilyl) Ester is a highly functionalized silicon-protected malonate derivative, serving as a critical reagent in advanced organic synthesis. Its primary value lies in its role as a versatile, protected synthon for the controlled introduction of malonic acid units under mild conditions, enabling complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for introducing malonate-derived fragments.
• Peptide Mimetics & Modifications: Used in the preparation of non-natural amino acids and peptide backbone modifications.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of silicon-containing polymers and hybrid materials.
• Organic Synthesis Reagent: Employed in Knoevenagel condensations, Michael additions, and other C-C bond-forming reactions under silyl-protecting group chemistry.
• Chemical Derivatization Agent: Used for the silylation of sensitive carboxylic acids and other functional groups in analytical chemistry.

Basic Information

Product Name	2-(Trimethylsilyl)-2-(Trimethylsiloxy)Malonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55530-65-9
Molecular Formula	C15H36O5Si4
Molecular Weight	420.81 g/mol
Synonyms	Bis(trimethylsilyl) 2-(trimethylsilyl)-2-(trimethylsiloxy)malonate; Malonic Acid, 2-(Trimethylsilyl)-2-(trimethylsiloxy)-, Bis(trimethylsilyl) Ester; 2-(Trimethylsilyl)-2-(trimethylsiloxy)malonic Acid Bis(trimethylsilyl) Ester; TMS-Malonic Acid Ester; Silylated Malonate Derivative; 1,3-Bis(trimethylsilyl) 2-(trimethylsilyl)-2-(trimethylsiloxy)propanedioate
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsilyl)-2-(Trimethylsiloxy)Malonic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results for purity, identity, and related substances are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.