Description

1-O,2-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Myo-Inositol 3-[Phosphoric Acid (Trimethylsilyl)[(R)-2,3-Bis[(Trimethylsilyl)Oxy]Propyl]] Ester is a highly functionalized, silyl-protected derivative of myo-inositol phosphate, designed for advanced synthetic and biochemical applications. This compound is a critical protected intermediate for the controlled synthesis of complex inositol phosphates and phospholipids, offering precise control over regiochemistry. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutics targeting cellular signaling pathways.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of phosphatidylinositol (PI) derivatives and inositol polyphosphate analogs used in drug discovery.
• Biochemical Research: Used in the study of inositol signaling pathways, enzyme substrates, and as a precursor for labeled (e.g., fluorescent or radioactive) inositol compounds.
• Glycoconjugate Synthesis: Serves as a protected scaffold for the development of complex glycophospholipids and other bioactive glycoconjugates.
• Lipidomics Standards: Can be utilized as a high-purity reference standard or calibration compound in mass spectrometry-based lipid analysis.
• Chemical Biology Probes: Enables the creation of cell-permeable probes to investigate the role of specific inositol phosphates in cellular processes.
• Advanced Material Science: Potential use as a functional monomer or cross-linker in the development of specialty polymers with unique properties.

Basic Information

Product Name	1-O,2-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Myo-Inositol 3-[Phosphoric Acid (Trimethylsilyl)[(R)-2,3-Bis[(Trimethylsilyl)Oxy]Propyl]] Ester
CAS No.	55528-10-4
Molecular Formula	C33H81O12PSi8
Molecular Weight	901.66 g/mol
Synonyms	D-myo-Inositol, 1,2,4,5,6-pentakis-O-(trimethylsilyl)-, 3-[phosphoric acid (trimethylsilyl)[(2R)-2,3-bis[(trimethylsilyl)oxy]propyl] ester]; 1,2,4,5,6-Penta-O-trimethylsilyl-myo-inositol 3-[P,O-bis(trimethylsilyl) (R)-2,3-bis(trimethylsilyloxy)propyl phosphate]; myo-Inositol, pentakis(trimethylsilyl) derivative, 3-phosphate ester; Protected myo-inositol phosphate intermediate; TMS-Inositol phosphate derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.