Description

3β-(Trimethylsiloxy)Stigmasta-5,24(28)-Diene is a high-purity, steroidal derivative featuring a trimethylsilyl (TMS) ether protecting group at the 3-beta position. This compound is a valuable synthetic intermediate and research chemical, prized for its role in the modification and study of sterol and steroid pathways. It is primarily utilized by research institutions and pharmaceutical development companies engaged in organic synthesis, medicinal chemistry, and the production of fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel therapeutic agents targeting hormone receptors or metabolic enzymes.
• Sterol Analog Synthesis: Serves as a precursor for creating modified sterols and stanols for biological evaluation and material science applications.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for the agrochemical and cosmetic industries.
• Reference Standard: Used as an analytical standard in chromatography (HPLC, GC) for quality control and method development in laboratories.
• Academic Research: A tool for studying organic reaction mechanisms, particularly those involving silyl protecting group chemistry and olefin transformations.

Basic Information

Product Name	3β-(Trimethylsiloxy)Stigmasta-5,24(28)-Diene
CAS No.	55527-94-1
Molecular Formula	C32H56OSi
Molecular Weight	484.88 g/mol
Synonyms	3β-(Trimethylsilyloxy)stigmasta-5,24(28)-diene; Stigmasta-5,24(28)-dien-3-ol, 3-(trimethylsilyl) ether, (3β)-; (3β)-3-[(Trimethylsilyl)oxy]stigmasta-5,24(28)-diene; 3β-TMS-Stigmasta-5,24(28)-diene; 3β-Trimethylsiloxy-Stigmasta-5,24(28)-Diene; 3β-Hydroxystigmasta-5,24(28)-diene trimethylsilyl ether; 24(28)-Dehydro-β-sitosterol trimethylsilyl ether; TMS ether of 24(28)-Dehydro-β-sitosterol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and fine chemical use. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity and purity. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.