Description

2-O,3-O,4-o-Tris(Trimethylsilyl)-β-D-Fructofuranose 1,6-Bis[Phosphoric Acid Bis(Trimethylsilyl)] Ester is a highly specialized, fully protected derivative of D-fructose, featuring multiple trimethylsilyl (TMS) groups. This compound is a critical intermediate in synthetic organic chemistry, valued for its role in the controlled synthesis of complex carbohydrates and nucleoside analogs where selective deprotection is required. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in advanced carbohydrate chemistry, glycobiology research, and the production of novel therapeutic agents.

Application

• Advanced Carbohydrate Synthesis: Serves as a key protected intermediate for the stepwise construction of oligosaccharides and complex sugar derivatives.
• Pharmaceutical Intermediate: Used in the research and development of nucleoside-based drugs, prodrugs, and other bioactive molecules containing modified sugar moieties.
• Glycobiology Research: Employed as a building block for synthesizing labeled or modified sugars to study biological recognition processes, enzyme mechanisms, and metabolic pathways.
• Chemical Biology Probe Development: Acts as a precursor for creating chemical probes to investigate carbohydrate-protein interactions and cellular signaling.
• Process Chemistry Development: Utilized in scaling up synthetic routes for carbohydrate-active pharmaceutical ingredients (APIs) under controlled, anhydrous conditions.

Basic Information

Product Name	2-O,3-O,4-o-Tris(Trimethylsilyl)-β-D-Fructofuranose 1,6-Bis[Phosphoric Acid Bis(Trimethylsilyl)] Ester
CAS No.	55521-25-0
Molecular Formula	C30H78O14P2Si7
Molecular Weight	933.62 g/mol
Synonyms	1,6-Bis[bis(trimethylsilyl)phosphoryl]-2,3,4-tris-O-(trimethylsilyl)-β-D-fructofuranose; β-D-Fructofuranose, 2,3,4-tris-O-(trimethylsilyl)-, 1,6-bis[dihydrogen (trimethylsilyl)phosphate] (ester); Fully Protected D-Fructose TMS Ester; TMS-Fructose Phosphoryl Ester; Hexakis(trimethylsilyl) Fructose Diphosphate Derivative; 55521-25-0; Fructose-1,6-bisphosphate TMS derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-O,3-O,4-o-Tris(Trimethylsilyl)-β-D-Fructofuranose 1,6-Bis[Phosphoric Acid Bis(Trimethylsilyl)] Ester is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to strict internal quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Ensure the storage area is well-ventilated and free from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.