Description

(9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid 2-Trimethylsilyloxy-1-[(Trimethylsilyloxy)Methyl]Ethyl Ester is a silylated derivative of α-linolenic acid, a key ω-3 fatty acid, designed to enhance stability and volatility for advanced analytical and synthetic applications. This compound is crucial for researchers and manufacturers requiring precise analysis or derivatization of polyunsaturated fatty acids (PUFAs) in complex matrices. It is primarily utilized in analytical chemistry, pharmaceutical research, and the development of high-value nutritional and cosmetic ingredients.

Application

• Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS) Analysis: Used as a derivatization agent to improve the volatility, thermal stability, and detection sensitivity of ω-3 fatty acids and other carboxylic acids in biological, food, and environmental samples.
• Pharmaceutical Intermediate: Serves as a protected synthetic intermediate in the research and development of novel pharmaceutical compounds, particularly those targeting lipid metabolism and inflammatory pathways.
• Nutritional Supplement Research: Employed in the analytical quantification and metabolic study of α-linolenic acid (ALA) and its derivatives in nutraceutical formulations and clinical research.
• Reference Standard: Acts as a high-purity certified reference material (CRM) for calibrating instruments and validating analytical methods in quality control laboratories.
• Organic Synthesis: Utilized as a building block in synthetic organic chemistry for the preparation of more complex, functionalized lipid molecules for material science and specialty chemicals.
• Cosmetic Ingredient Development: Applied in R&D for stabilizing and delivering sensitive fatty acid actives in advanced skincare and cosmetic formulations.

Basic Information

Product Name	(9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid 2-Trimethylsilyloxy-1-[(Trimethylsilyloxy)Methyl]Ethyl Ester
CAS No.	55521-23-8
Molecular Formula	C27H54O5Si2
Molecular Weight	514.89 g/mol
Synonyms	α-Linolenic Acid Bis(trimethylsilyl) Glycerol Ester; Glycerol 1,3-Bis(trimethylsilyl) Ether 2-α-Linolenate; 1,3-Bis-O-(trimethylsilyl)-2-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]glycerol; ALA Bis-TMS Derivative; Linolenic Acid 1,3-Bis(trimethylsilyl) Glyceride; (9Z,12Z,15Z)-Octadecatrienoic Acid 1,3-Bis(trimethylsilyl)-2-propyl Ester; 2-[(9Z,12Z,15Z)-9,12,15-Octadecatrienoyloxy]-1,3-bis(trimethylsiloxy)propane
EINECS	Contact for details

Quality Control

Our (9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid 2-Trimethylsilyloxy-1-[(Trimethylsilyloxy)Methyl]Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.