Description

(9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid 2,3-Bis(Trimethylsilyloxy)Propyl Ester is a chemically modified derivative of α-linolenic acid (ALA), a key ω-3 fatty acid, where the carboxylic acid group is protected as a silyl ester. This compound matters as a crucial protected intermediate in organic synthesis, enabling the manipulation of the sensitive polyunsaturated chain without degradation. It is primarily needed by research and development laboratories in the pharmaceutical, nutraceutical, and specialty chemical sectors for the synthesis of complex lipids, prodrugs, and bioactive molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel lipid-based drug candidates and prodrugs targeting metabolic and inflammatory pathways.
• Biochemical Research: Serves as a protected building block for studying the biological roles and metabolic fate of ω-3 fatty acids.
• Nutraceutical Development: Acts as a key precursor in the development of advanced, stabilized ω-3 formulations with enhanced bioavailability.
• Organic Synthesis: Employed as a versatile intermediate for constructing complex, polyunsaturated molecular architectures in total synthesis projects.
• Reference Standard: Utilized as an analytical standard in chromatography (GC, HPLC) for method development and quality control of related compounds.
• Material Science: Potential use in the synthesis of functionalized polymers and surface-modifying agents.

Basic Information

Product Name	(9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid 2,3-Bis(Trimethylsilyloxy)Propyl Ester
CAS No.	55521-22-7
Molecular Formula	C27H54O5Si2
Molecular Weight	514.89 g/mol
Synonyms	α-Linolenic Acid 2,3-Bis(trimethylsilyloxy)propyl Ester; ALA-TMS Ester; 9Z,12Z,15Z-Octadecatrienoic Acid 2,3-Bis[(trimethylsilyl)oxy]propyl Ester; (all-Z)-9,12,15-Octadecatrienoic Acid 2,3-Bis(trimethylsiloxy)propyl Ester; Propane-1,2,3-triyl Tris(trimethylsilyl) Ether Linolenate; Linolenic Acid Tris(trimethylsilyl) Glycerol Ester; Glycerol Tris(trimethylsilyl) Ether Linolenate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a cGMP-compliant quality management system for consistent, reliable supply to research and development markets.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. For long-term storage, keep at -20°C. The container should be kept in a cool, dry, and well-ventilated area separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.