Description

n-(3-Methyl-1-Oxobutyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in enabling complex peptide and heterocycle construction by protecting the glycine moiety, which facilitates challenging coupling reactions and prevents unwanted side reactions. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and protease inhibitors.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides with specific amino acid backbones.
• Peptide Chemistry: Serves as a protected glycine equivalent in solid-phase and solution-phase peptide synthesis (SPPS).
• Organometallic & Catalysis Research: Employed as a ligand precursor or a modifying agent in catalyst design.
• Chemical Biology Probes: Utilized in the development of labeled amino acids for studying biological pathways.
• Material Science: Potential monomer for creating specialized silicon-containing polymers.

Basic Information

Product Name	n-(3-Methyl-1-Oxobutyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester
CAS No.	55520-90-6
Molecular Formula	C13H27NO3Si2
Molecular Weight	301.53 g/mol
Synonyms	N-(3-Methyl-1-oxobutyl)-N-(trimethylsilyl)glycine trimethylsilyl ester; N-Isovaleryl-N-(trimethylsilyl)glycine trimethylsilyl ester; Trimethylsilyl N-[N-(trimethylsilyl)isovalerylglycinate]; N-(Trimethylsilyl)-N-isovalerylglycine trimethylsilyl ester; IVG-TMS; Isovaleryl-glycine bis(trimethylsilyl) derivative; TMS-Gly-Isovaleryl TMS ester; Silylated isovaleryl glycine derivative
EINECS	Contact for details

Quality Control

Our production of n-(3-Methyl-1-Oxobutyl)-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.