Description

Trimethylsilyl 3-Deoxy-2,4,5-Tris-o-(Trimethylsilyl)-2-C-([(Trimethylsilyl)Oxy]Methyl)Pentonate is a highly functionalized, multi-silylated carbohydrate derivative used as a critical protected intermediate in advanced organic synthesis. Its value lies in providing multiple points of controlled reactivity, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleosides and nucleotide analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for the stepwise, regioselective construction of complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Used in the production of specialty chemicals where precise control over stereochemistry and functional group manipulation is required.
• Process Chemistry Development: Enables scalable synthetic routes for active pharmaceutical ingredients (APIs) by providing a stable, reactive intermediate.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	Trimethylsilyl 3-Deoxy-2,4,5-Tris-o-(Trimethylsilyl)-2-C-([(Trimethylsilyl)Oxy]Methyl)Pentonate
CAS No.	55517-79-8
Molecular Formula	C22H52O6Si5
Molecular Weight	573.11 g/mol
Synonyms	3-Deoxy-2,4,5-tris-O-(trimethylsilyl)-2-C-[(trimethylsilyloxy)methyl]pentonic acid trimethylsilyl ester; Trimethylsilyl 3-deoxy-2,4,5-tris-O-(trimethylsilyl)-2-C-[(trimethylsilyloxy)methyl]pentonate; 2-C-[(Trimethylsilyloxy)methyl]-3-deoxy-2,4,5-tris-O-(trimethylsilyl)pentonic acid trimethylsilyl ester; Fully silylated pentonate derivative; TMS-protected pentonate
EINECS	Contact for details

Quality Control

Our Trimethylsilyl 3-Deoxy-2,4,5-Tris-o-(Trimethylsilyl)-2-C-([(Trimethylsilyl)Oxy]Methyl)Pentonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C) and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.