Description

5-Methoxy-2-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester is a high-purity, protected benzoic acid derivative primarily used as a key synthetic intermediate in advanced organic chemistry. Its dual silyl protection makes it a valuable reagent for introducing the 5-methoxysalicylate moiety under controlled conditions, offering enhanced stability and selectivity in sensitive reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, particularly those requiring protected salicylate or benzoate frameworks.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating specialty chemicals, agrochemicals, and advanced materials.
• Research & Development: Serves as a protected precursor in medicinal chemistry and process chemistry research for exploring new synthetic pathways.
• API Manufacturing: Employed in the controlled, large-scale production of active pharmaceutical ingredients where specific functional group protection is required.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of specialized ligands or catalyst components for asymmetric synthesis.

Basic Information

Item	Details
Product Name	5-Methoxy-2-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester
CAS No.	55517-47-0
Molecular Formula	C14H24O4Si2
Molecular Weight	312.51 g/mol
Synonyms	5-Methoxy-2-(trimethylsiloxy)benzoic acid TMS ester; 2-Hydroxy-5-methoxybenzoic acid bis(trimethylsilyl) ether; Bis(trimethylsilyl) 5-methoxysalicylate; 5-Methoxysalicylic acid bis(trimethylsilyl) ester; TMS-5-Methoxysalicylate; 55517-47-0; Benzoic acid, 5-methoxy-2-(trimethylsiloxy)-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.