Description

(2E,4E)-2,4-Hexadienedioic Acid Bis(Trimethylsilyl) Ester is a silylated derivative of muconic acid, serving as a versatile and protected synthetic intermediate. Its primary value lies in enabling advanced organic synthesis, particularly in the preparation of complex molecules where sensitive functional groups require protection from harsh reaction conditions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to streamline multi-step syntheses.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly where the diacid functionality needs temporary protection.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or co-monomer precursor for developing specialized polymers, coatings, and resins with unique properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, Diels-Alder chemistry, and as a precursor for other functionalized diene compounds.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of specific aroma chemicals and flavoring agents.

Basic Information

Product Name	(2E,4E)-2,4-Hexadienedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	55517-43-6
Molecular Formula	C12H24O4Si2
Molecular Weight	288.49 g/mol
Synonyms	Muconic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) (2E,4E)-Hexa-2,4-dienedioate; (E,E)-Muconic Acid Bis-O-(trimethylsilyl) Ester; 2,4-Hexadienedioic Acid, Bis(trimethylsilyl) Ester; TMS-Muconate; Trimethylsilyl Muconate; Hexadienedioic Acid Bis(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our (2E,4E)-2,4-Hexadienedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.